Nina Pickering Season 3

During her first transformation at their new home, Nina and George apparently have sex while in wolf form, despite George's belief that one of them would kill the other if they transformed in close proximity to each other. She later assists George in helping the permanently teenage vampire Adam, the two briefly contemplating taking over responsibility for Adam after his parents' deaths from old age before Adam departs to make his own way, wanting to explore his own independence without being a burden on them like he was on his parents. After learning that she was pregnant as a result of her and George's intercourse while in wolf form, Nina admits that her mother abused her when she was a child, contemplating terminating the pregnancy both because she fears the consequences of two werewolves creating a child and because she is afraid of repeating her mother's treatment of her. However, after the 'zombie' Sasha admitted that her only regret was missing so many moments in life because she was more focused on the present than the future, Nina decided to keep the baby. Although they have not yet been able to determine what the baby will look like when born, or if it will 'inherit' the werewolf 'gene', Nina has apparently kept the baby despite the stress of her first pregnant transformation, although it is unclear how this will work as her condition progresses. Following a confrontation between Mitchell and Nina over Herrick's fate, along with Herrick's subsequent discovery of a 'diary' of Mitchell's recent murders, Mitchell has begun to suspect that Nina is the werewolf that is 'prophesied' to kill him.

When George and Nina arranged an ultrasound to examine their baby, the nurse carrying out the operation noted that Nina appeared to be sixteen weeks along rather than the eight she believed, but George speculated that this was just the result of werewolves gestating faster than humans, much like conventional wolves. However, Nina was subsequently stabbed by the now-restored Herrick after Mitchell was arrested by the police, Herrick wanting to make George suffer like he did when George killed him, expressing regret at attacking and stabbing Nina after she was the only person in the house to show him kindness. Fortunately, Annie was able to convince Lia to help her save Nina and the baby after convincing her that revenge couldn't solve anything.

John Mitchell Season 3

When Mitchell enters Purgatory to rescue Annie – following a terminally ill patient at the hospital where George and Nina now work through the Door after his demise -, he learns that the time and date of his death has been confirmed, and he will be killed by a werewolf at some unspecified- but apparently not-too-distant- future date, although he later comments to Annie that he doesn't believe a word of what he heard. Although haunted by both the 'prophecy' of his death and the continued police hunt for the person responsible for the 'Box Tunnel Twenty' massacre, Mitchell rejected an offer to depart Britain to live with the vampire 'Old Ones', commenting during a talk with permanently teenage vampire Adam that his friends help him remain clean as their goodness inspires him by forcing him to think about the disappointment they would feel if he succumbed to his thirst. After a confrontation with vampire 'fan' Graham, Mitchell tried to tell Annie the truth about the tunnel massacre, but Annie simply told him that whatever he had to tell her didn't matter, assuring him that all she wanted was the man he was now and that what he'd done in the past didn't matter compared to what he'd done for her and George, the two subsequently kissing. Although Annie tries to find ways for their relationship to become physical at first, Mitchell admits that he actually prefers their current bond, as sex has always been about violence rather than love with him, and he prefers for his relationship with Annie to be 'pure' and apart from that.

Despite some tension with werewolf vampire-hunter McNair due to Mitchell's concerns regarding the 'prophecy' of his death- although he claims to Annie that he doesn't believe in fate-, Mitchell and McNair reached a certain understanding when they worked together to save George and Nina from a group of vampires, although McNair still feels that Mitchell's sins will catch up to him eventually. When Herrick returns to life, Mitchell initially attempts to stake him- particularly after Cara stakes herself before she can tell Mitchell how she and Daisy brought Herrick back-, but is convinced by George to let Herrick live on the grounds that he deserves the same chances everyone has given Mitchell. When Annie learns about Mitchell's role in the massacre, she tearfully convinced him to allow himself to be arrested, Mitchell going along with it to prove his love for her even as he tries to escape being processed due to the risks if his true nature is exposed.

Although Herrick released Mitchell- revealing in the process that his resurrection was aided by the fact that he was torn apart rather than just being staked-, Mitchell finally staked Herrick when he concluded that he had seen and done enough in his life. With the news that another man had been framed for the Box Tunnel Twenty he returned to the house to ask George to kill him, recognising that whoever had set up that frame would want a favour later and wanting to free his friends of the taint he had brought to their lives. He is then killed by George, after The Old Ones' attempt to use Mitchell to do their dirty work (work spelled out by old one Wyndham). George's last words to Mitchell are: "I'm doing this because I love you", to which Mitchell responds "I know".

Annie Sawyer Season 3

Trailing series 3, Annie appeared in a series of videos on the BBC website, sending messages from the other side. In the final one, viewers saw that she was being sent to hell, with the gatekeepers making a special room for her and burning the key. However, she is subsequently permitted to leave with Mitchell when he enters Purgatory to recover her. Lia – Mitchell's spiritual guide- informs her that the complications were caused by her entering the afterlife through the 'wrong door', although noting that she will still have to come back through the right one eventually. Upon returning from Purgatory, Annie is reunited with George and Nina in the quartet's new home in Barry Island, Wales.

Overwhelmed with gratitude to Mitchell for having rescuing her, Annie begins to fall for him and appoints herself as his guardian angel. Although her first attempts at helping him end in disaster, she manages to get him a job. On a celebratory walk on the seafront, Mitchell tells her she must stop defining herself by what she does for other people, but Annie opposes this, expressing that it was he, George and Nina that she came back for and that if it wasn't for them she might as well be in Purgatory. After learning that Mitchell's journey into Purgatory to rescue her had resulted in the creation of at least five zombie-like beings – dead bodies who nevertheless continued walking and talking – Annie attempted to help Sasha, the last surviving 'zombie', adapt to her current state. She providing Sasha with a makeover to conceal the worst of her decay, and when this failed, remained with Sasha as her body finally collapses. After this, Mitchell's resistance to Annie's love weakens, and he attempts to tell her the truth about his recent actions (including the Box Tunnel Massacre). Annie stops him before he can confess, assuring him that – regardless of the terrible things he'd done in his past – all she cares about was the man he was now. The two subsequently kiss and embark on a full partnership.

However, attempts by Annie and Mitchell to develop a sex life are unsuccessful. Annie attempts to bypass the problem by suggesting that Mitchell has a one-night-stand while Annie 'shares' the experience with the woman. This plan backfires when Mitchell's vampire instincts take over and he attempts to drain the woman's blood, although he stops himself. After sending the woman away, he admits to Annie that he's actually content to have a non-physical relationship with her (as sex has always been about violence with him rather than love) and that he regards their relationship as something 'pure'. Things took a turn for the worse when Annie finally learned that Mitchell had been involved in the Box Tunnel 20 Massacre. Devastated, she convinced Mitchell to let himself be arrested despite the wider dangers if his true nature is discovered.

In the third series final, Annie learns of Mitchell's "wolf-shaped bullet" and that it was the price of her return. After discovering Nina injured in the hospital and receiving a message from the other side, she returns to purgatory in the hopes of sacrificing herself to repel the prophecy, but learns from Lia that there was never any prophecy at all. Lia intends to keep Annie in purgatory in order to deprive Mitchell of her – Lia's true revenge on Mitchell. Annie also witnesses the fight Herrick had stirred up between George and Mitchell, and Lia informs her that Mitchell had fulfilled the nonexistent prophecy himself. Annie concludes that Nina must still be alive as she has not passed over, and convinces Lia that her revenge is unjust. Lia allows Annie to depart, and Annie arrives back in the hospital to find Nina alive and still carrying the baby.

Back at the house, Annie, George and Nina find a blood-soaked Mitchell on their doorstep. Mitchell persuades George to kill him and bids farewell to Annie with the words "You were the love of my long life". She replies that he is the love of hers, but before George can stake Mitchell, Wyndall appears and announces that the vampires are taking control of the world. He implies that Annie is a lot stronger than she imagines. But when he says that Mitchell will be used to kill for him, George stakes Mitchell in the heart. Annie, George and Nina watch as their vampire friend disintegrates, then stand together as they warn Wyndall that he has a fight on his hands.